Can a grid of radiation beams shrink tumors that resist standard treatment?
NCT ID NCT07774819
First seen Aug 19, 2026 · Last updated Aug 19, 2026
Summary
This trial is investigating whether spatially fractionated radiotherapy, a technique that delivers radiation in a grid-like pattern, can safely and effectively treat bulky (larger than 4 cm) or refractory solid tumors. The study will measure how many patients complete the treatment without severe side effects and how many tumors shrink or disappear. It aims to find out if this approach can help when standard radiation has failed or is not an option.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- spatially fractionated radiotherapy (a type of radiation therapy that delivers high doses in a grid-like pattern)
- What this could lead to
- If successful, this approach could offer a new treatment option for large or hard-to-treat tumors that do not respond to standard radiation, potentially improving tumor control and survival.
- What could go wrong
- This is an early-phase trial, so the benefits are uncertain. The treatment may cause significant side effects, including bleeding or perforation, especially in tumors near hollow organs, and it may not work for all patients.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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The University of Hong Kong - Shenzhen Hospital
RECRUITINGShenzhen, Guangdong, 518053, China
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