New drug shows promise in slowing rare kidney disease

NCT ID NCT03762850

Ongoing Disease control Sponsor: Travere Therapeutics, Inc. Source: ClinicalTrials.gov ↗

First seen Apr 25, 2026 · Last updated Apr 28, 2026 · Updated 1 time

Summary

This study tests a new medicine called sparsentan for people with IgA nephropathy, a kidney disease that can lead to kidney failure. About 400 adults with the condition took either sparsentan or a standard blood pressure drug for 2 years. The goal was to see if sparsentan better protects kidney function and reduces protein in urine, a sign of kidney damage.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Locations

Travere Investigational Site

Birmingham, Alabama, 35233, United States
Travere Investigational Site

Homewood, Alabama, 35209, United States
Travere Investigational Site

Glendale, California, 91206, United States
Travere Investigational Site

Montebello, California, 90640, United States
Travere Investigational Site

Northridge, California, 91324, United States
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San Diego, California, 92103-6204, United States
Travere Investigational Site

San Diego, California, 92103, United States
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Stanford, California, 94205, United States
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Denver, Colorado, 80230, United States
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Coral Springs, Florida, 33071, United States
Travere Investigational Site

Hollywood, Florida, 33021, United States
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Miami, Florida, 33136, United States
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Miami, Florida, 33186, United States
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Winter Park, Florida, 32789, United States
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Lawrenceville, Georgia, 30046, United States
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Nampa, Idaho, 83687, United States
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Hinsdale, Illinois, 60521, United States
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Muncie, Indiana, 47303, United States
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Kansas City, Kansas, 66160, United States
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Louisville, Kentucky, 40202, United States
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Boston, Massachusetts, 02215, United States
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Springfield, Massachusetts, 01104, United States
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Worcester, Massachusetts, 01608, United States
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Minneapolis, Minnesota, 55404, United States
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Reno, Nevada, 89511, United States
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Fresh Meadows, New York, 11365, United States
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New York, New York, 10032, United States
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Cleveland, Ohio, 44106, United States
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Columbus, Ohio, 43210, United States
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Philadelphia, Pennsylvania, 19104, United States
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Columbia, South Carolina, 29203, United States
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El Paso, Texas, 79935, United States
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Fort Worth, Texas, 76104, United States
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Houston, Texas, 77054, United States
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Lewisville, Texas, 75057, United States
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San Antonio, Texas, 78207, United States
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Salt Lake City, Utah, 84115, United States
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Salt Lake City, Utah, 84132, United States
Travere Investigational Site

Tacoma, Washington, 98405, United States
Travere Investigational Site

Marshfield, Wisconsin, 54449, United States
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Concord, New South Wales, 2139, Australia
Travere Investigational Site

Gosford, New South Wales, 2250, Australia
Travere Investigational Site

Kingswood, New South Wales, 2747, Australia
Travere Investigational Site

New Lambton Heights, New South Wales, 2305, Australia
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Randwick, New South Wales, 2031, Australia
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St Leonards, New South Wales, 2065, Australia
Travere Investigational Site

Birtinya, Queensland, 4575, Australia
Travere Investigational Site

Adelaide, South Australia, 5000, Australia
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Reservoir, Victoria, 3073, Australia
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Nedlands, Western Australia, 6009, Australia
Travere Investigational Site

Bonheiden, 2820, Belgium
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Bruges, 8310, Belgium
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Ghent, 9000, Belgium
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Kortrijk, 8500, Belgium
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Liège, 4000, Belgium
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Roeselare, 8800, Belgium
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Osijek, 31000, Croatia
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Zagreb, 10000, Croatia
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Prague, 10034, Czechia
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Prague, 12808, Czechia
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Tallinn, 10617, Estonia
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Tallinn, 13419, Estonia
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Tartu, 50406, Estonia
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Marseille, Bouches-du-Rhone, 13005, France
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Montpellier, Herault, 34295, France
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Grenoble, Isere, 38043, France
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Paris, Paris, 75015, France
Travere Investigational Site

Saint-Priest-en-Jarez, Pays de la Loire Region, 42270, France
Travere Investigational Site

Clermont-Ferrand, Puy De Dome, 63003, France
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Créteil, 94010, France
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Paris, 75475, France
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Villingen-Schwenningen, Baden-Wurttemberg, 78052, Germany
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Hanover, Lower Saxony, 30625, Germany
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Aachen, North Rhine-Westphalia, 52074, Germany
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Düsseldorf, North Rhine-Westphalia, 40210, Germany
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Kaiserslautern, Rheinland Palatinate, 67655, Germany
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Trier, Rheinland Palatinate, 54292, Germany
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Kiel, Schleswig-Holstein, 23538, Germany
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Kiel, Schleswig-Holstein, 24105, Germany
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Jena, Thuringia, 07747, Germany
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Berlin, 10117, Germany
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Kwun Tong, Kowloon, Hong Kong
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Lai Chi Kok, Kowloon, Hong Kong
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Shatin, New Territories, Hong Kong
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Tsuen Wan, New Territories, Hong Kong
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Hong Kong, Hong Kong
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Ranica, Bergamo, 24020, Italy
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Milan, Lombardy, 20162, Italy
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Bari, 70124, Italy
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Catania, 95123, Italy
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Catanzaro, 88100, Italy
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Lecco, 23900, Italy
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Modena, 41124, Italy
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Pavia, 27100, Italy
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Roma, 00168, Italy
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Torino, 10126, Italy
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Kaunas, LT-50009, Lithuania
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Vilnius, LT-08661, Lithuania
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Grafton, Auckland, 1142, New Zealand
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Hamilton, 3200, New Zealand
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Hastings, 4120, New Zealand
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New Plymouth, 4310, New Zealand
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Krakow, 31-559, Poland
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Lodz, 93-347, Poland
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Olsztyn, 10-124, Poland
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Olsztyn, 10-561, Poland
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Warsaw, 04-749, Poland
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Wroclaw, 50-566, Poland
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Coimbra, 3000-075, Portugal
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Lisbon, 1069-166, Portugal
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Lisbon, 1649-035, Portugal
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Loures, 2674-514, Portugal
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Setúbal, 2910-446, Portugal
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Vila Nova de Gaia, 4434-502, Portugal
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Seongnam-si, Gyeonggi-do, 13620, South Korea
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Anyang-si, 14068, South Korea
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Busan, 47392, South Korea
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Incheon, 21565, South Korea
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Seoul, 02841, South Korea
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Seoul, 03080, South Korea
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Seoul, 06273, South Korea
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Seoul, 110-746, South Korea
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Seoul, 120-752, South Korea
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Seoul, 135-710, South Korea
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Palma de Mallorca, Balearic Islands, 07120, Spain
Travere Investigational Site

Sagunto, Valencia, 46520, Spain
Travere Investigational Site

Barcelona, 08003, Spain
Travere Investigational Site

Barcelona, 08025, Spain
Travere Investigational Site

Barcelona, 08035, Spain
Travere Investigational Site

Barcelona, 08036, Spain
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Madrid, 28007, Spain
Travere Investigational Site

Madrid, 28040, Spain
Travere Investigational Site

Madrid, 28041, Spain
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Seville, 41009, Spain
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Valencia, 46014, Spain
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Valencia, 46017, Spain
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Zaragoza, 50009, Spain
Travere Investigational Site

Hualien City, 970, Taiwan
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Kaohsiung City, 807, Taiwan
Travere Investigational Site

Kaohsiung City, 81362, Taiwan
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New Taipei City, 220, Taiwan
Travere Investigational Site

Taichung, 40705, Taiwan
Travere Investigational Site

Reading, Berkshire, RG1 5AN, United Kingdom
Travere Investigational Site

Cambridge, Cambridgeshire, CB2 0QQ, United Kingdom
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Middlesbrough, Cleveland, TS4 3BW, United Kingdom
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Derby, Derbyshire, DE22 3DT, United Kingdom
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Brighton, East Sussex, BN2 5BE, United Kingdom
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London, Greater London, E1 4AT, United Kingdom
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London, Greater London, SE1 9RT, United Kingdom
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Manchester, Greater Manchester, M13 9WL, United Kingdom
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Salford, Greater Manchester, M6 8HD, United Kingdom
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Preston, Lancashire, PR2 9HT, United Kingdom
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Leicester, Leicestershire, LE5 4PW, United Kingdom
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Edinburgh, Scotland, EH16 4SA, United Kingdom
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Stoke-on-Trent, Staffordshire, ST4 6QG, United Kingdom
Travere Investigational Site

Glasgow, Strathclyde, G11 6NT, United Kingdom
Travere Investigational Site

Carshalton, Surrey, SM5 1AA, United Kingdom
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Cardiff, West Glamorgan, CF14 4XW, United Kingdom
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Birmingham, West Midlands, B9 5SS, United Kingdom
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Liverpool, L9 7AL, United Kingdom
Travere Investigational Site

London, E1 1FR, United Kingdom
Travere Investigational Site

London, SE5 9RS, United Kingdom

Conditions

Explore the condition pages connected to this study.

IMMUNOGLOBULIN A NEPHROPATHY IMMUNOGLOBULIN A NEPHROPATHY