Digital exercise: a new weapon against joint inflammation?
NCT ID NCT06462937
First seen Aug 20, 2026 · Last updated Aug 21, 2026 · Updated 1 time
Summary
This trial tests whether a remotely supervised exercise program can reduce disease activity in people recently diagnosed with axial spondyloarthritis, a type of inflammatory arthritis affecting the spine and joints. Participants will follow a personalized plan with high-intensity interval training, strength exercises, and aerobic activity, delivered through a smartphone app. The study compares digitally supervised exercise to unsupervised exercise, measuring how many people achieve low disease activity after three months.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- A remotely delivered exercise program with digital supervision, including high-intensity interval training, strength exercises, and aerobic activity, plus educational videos.
- What this could lead to
- If effective, this could offer a scalable, accessible way to manage disease activity in spondyloarthritis, potentially reducing the need for biologic medications.
- What could go wrong
- The trial is relatively small and the outcome depends on adherence to the exercise program. Exercise may not be sufficient for all patients, and some may not tolerate high-intensity training.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 260 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Jul 2024
- Expected to finish
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Aug 2030
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * axSpA diagnosis within the last two years by a rheumatologist according to the ASAS criteria of 2009 * active disease (ASDAS \> 1.3) Exclusion Criteria: * Active uveitis. * CRP \> 30. * Former or current use of bDMARDs. * Pregnancy or planned pregnancy within 6 months from inclusion. * Absolute and relative contradictions to high intensity exercise according to the American College of Sports Medicine (ACSM) * Other serious disease such as cancer. * Patients incapable to follow the protocol or the control set-up with remote monitoring.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Diakonhjemmet hospital
RECRUITINGOslo, Norway
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