Could a new pill rewire depressed brains? early trial begins

NCT ID NCT06570369

First seen Oct 31, 2025 · Last updated May 14, 2026 · Updated 31 times

Summary

This early-stage study tests an experimental drug called SP-624 in 36 adults—some healthy and some with major depression. Participants take the drug or a placebo daily for two weeks. Researchers use EEG brain scans and AI to see if SP-624 changes brain activity and improves memory. The main goal is safety and understanding how the drug affects the brain.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Alivation Research

    COMPLETED

    Lincoln, Nebraska, 68526, United States

  • CenExel CNS

    RECRUITING

    Garden Grove, California, 92845, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.