New drug switch may stall lung cancer in High-Risk patients
NCT ID NCT06333678
First seen Nov 01, 2025 · Last updated May 09, 2026 · Updated 25 times
Summary
This study looked at whether switching from durvalumab to sotorasib can better control locally advanced non-small cell lung cancer in people with a KRAS G12C mutation who still have signs of cancer after chemoradiation. Ten participants were randomly assigned to either switch to sotorasib or stay on durvalumab. The goal was to see if the switch could delay cancer growth or death.
Disclaimer
Read more
Show less
This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for NON-SMALL CELL LUNG CANCER are added.
By submitting, you agree to our Terms of use
Contacts and locations
Show contact details
Enter your email to view the contact information for this study.
By submitting, you agree to our Terms of use
Locations
-
Memorial Sloan Kettering Basking Ridge (All Protocol Activities)
Basking Ridge, New Jersey, 07920, United States
-
Memorial Sloan Kettering Bergen (All Protocol Activities)
Montvale, New Jersey, 07645, United States
-
Memorial Sloan Kettering Cancer Center (All Protocol Activities)
New York, New York, 10065, United States
-
Memorial Sloan Kettering Monmouth (All Protocol Activities)
Middletown, New Jersey, 07748, United States
-
Memorial Sloan Kettering Nassau (All Protocol Activities)
Uniondale, New York, 11553, United States
-
Memorial Sloan Kettering Suffolk - Commack (All Protocol Activities)
Commack, New York, 11725, United States
-
Memorial Sloan Kettering Westchester (All Protocol Activities)
Harrison, New York, 10604, United States
-
University of Miami (Data Collection Only)
Miami, Florida, 33136, United States
-
University of Michigan (Data Collection Only)
Ann Arbor, Michigan, 48109, United States
-
Vanderbilt University (Data Collection Only)
Nashville, Tennessee, 37232, United States
Conditions
Explore the condition pages connected to this study.