New pill shows promise in Hard-to-Treat blood cancer
NCT ID NCT06561048
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This phase 3 trial tests a new oral drug, soquelitinib, against standard single-agent chemotherapy in 150 adults with relapsed or refractory peripheral T-cell lymphoma. The study aims to see if soquelitinib can delay cancer progression better than current options. Participants are randomly assigned to receive either soquelitinib or a standard drug chosen by their doctor.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Soquelitinib (an ITK inhibitor taken as a pill)
What this could lead to
If successful, soquelitinib could offer a new, more targeted treatment option for people with certain types of T-cell lymphoma that have not responded to prior therapy.
What could go wrong
This is a phase 3 trial, but it is still experimental. The drug may not prove more effective than existing treatments, and side effects are possible. Results may not apply to all lymphoma subtypes.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
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Austin Hospital
RECRUITINGHeidelberg, Victoria, 3084, Australia
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BC Cancer Research Institute
RECRUITINGVancouver, British Columbia, V5Z4E6, Canada
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Box Hill Hospital
RECRUITINGBox Hill, Victoria, 3128, Australia
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City of Hope National Medical Center
RECRUITINGDuarte, California, 91010, United States
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Emory University
RECRUITINGAtlanta, Georgia, 30322, United States
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Epworth Healthcare
RECRUITINGRichmond, Victoria, 3121, Australia
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Flinders Medical Center
RECRUITINGBedford Park, South Australia, 5042, Australia
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Hackensack University Medical Center
RECRUITINGHackensack, New Jersey, 07601, United States
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ICON Cancer Centre
RECRUITINGSouth Brisbane, Queensland, 4101, Australia
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Icahn School of Medicine at Mount Sinai
RECRUITINGNew York, New York, 10029, United States
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Linear Clinical Research
RECRUITINGPerth, Western Australia, 6009, Australia
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MD Anderson Cancer Center
RECRUITINGHouston, Texas, 77030, United States
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Massachusetts General Hospital
RECRUITINGBoston, Massachusetts, 02114, United States
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Memorial Sloan Kettering Cancer Center
RECRUITINGNew York, New York, 10065, United States
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North Carolina Cancer Hospital
RECRUITINGChapel Hill, North Carolina, 27514, United States
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North Western University Robert H. Lurie Comprehensive Cancer Center RHLCCC
RECRUITINGChicago, Illinois, 60611, United States
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Roger Cancer Center University of Michigan Health
RECRUITINGAnn Arbor, Michigan, 48109, United States
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Royal Adelaide Hospital
RECRUITINGAdelaide, South Australia, 5000, Australia
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Royal Hobart Hospital
RECRUITINGHobart, Tasmania, 7000, Australia
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St George Hospital
RECRUITINGKogarah, New South Wales, 2217, Australia
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St Vincent's Hospital Sydney
RECRUITINGDarlinghurst, New South Wales, 2010, Australia
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Sylvester Comprehensive Cancer Center University of Miami Miller School of Medicine
RECRUITINGMiami, Florida, 33136, United States
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The Ohio State University
RECRUITINGColumbus, Ohio, 43210, United States
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The Ottawa Hospital - General Campus
RECRUITINGOttawa, Ontario, K1H8L6, Canada
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The Princess Margaret Cancer Centre
RECRUITINGToronto, Ontario, M5G2C4, Canada
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University of California San Francisco
RECRUITINGSan Francisco, California, 94143, United States
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University of California, Irvine
RECRUITINGIrvine, California, 92697, United States
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University of Iowa
RECRUITINGIowa City, Iowa, 52242, United States
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University of Maryland Medical Center
RECRUITINGBaltimore, Maryland, 21201, United States
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University of Washington Fred Hutch Cancer Center
RECRUITINGSeattle, Washington, 98109, United States
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University of Wisconsin Carbone Cancer Center
RECRUITINGMadison, Wisconsin, 53792, United States
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Washington University in St. Louis
RECRUITINGSt Louis, Missouri, 63130, United States
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Weill Cornell Medicine
RECRUITINGNew York, New York, 10065, United States
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Yale University
RECRUITINGNew Haven, Connecticut, 06520, United States
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