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Engineered immune cells take aim at hard-to-treat blood cancers

NCT ID NCT06699771

Recruiting now ⭐️ CURE ⭐️ Sponsor: GC Cell Corporation Source: ClinicalTrials.gov ↗

First seen Jul 24, 2026 · Last updated Jul 24, 2026

Summary

This early-phase trial is testing an experimental therapy called GCC2005, which uses a patient's own immune cells (natural killer cells) engineered to recognize and attack cancer cells. The study enrolls adults with NK or T-cell cancers that have returned or not responded to at least two prior treatments. Participants receive GCC2005 along with chemotherapy to prepare the body, and researchers monitor safety, side effects, and any signs of tumor shrinkage.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
an experimental CAR-NK cell therapy called GCC2005, given with lymphodepleting chemotherapy
What this could lead to
If successful, this could point toward a new treatment option for people with hard-to-treat NK and T-cell cancers.
What could go wrong
This is an early, first-in-human phase 1 trial with a small number of participants. Safety and effectiveness are not yet known, and there may be serious side effects.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

T-cell non-Hodgkin lymphoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

LYMPHOMA, T-CELL

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Asan Medical Center

    RECRUITING

    Seoul, Seoul, 05505, South Korea

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Samsung Medical Center

    RECRUITING

    Seoul, Seoul, 06351, South Korea

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Seoul National University Hosptial

    RECRUITING

    Seoul, Seoul, 03080, South Korea

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

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