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New hope for tough lymphomas: experimental drug STP938 enters human trials

NCT ID NCT05463263

Recruiting now Disease control Sponsor: Step Pharma, SAS Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study is for adults with B-cell or T-cell lymphoma that has returned or stopped responding to at least two prior treatments. The drug, STP938, blocks a protein cancer cells need to grow. The trial has two parts: first, finding a safe dose (Phase 1), then testing how well it shrinks tumors in different lymphoma types (Phase 2). About 180 people will take part.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

B-cell neoplasm B-cell non-Hodgkin lymphoma T-cell non-Hodgkin lymphoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

LYMPHOMA, B-CELL LYMPHOMA, T-CELL

Contacts and locations

Locations

  • CHU de Nantes

    RECRUITING

    Nantes, France

  • Churchill Hospital

    RECRUITING

    Oxford, United Kingdom

  • Colorado Blood Cancer Institute

    RECRUITING

    Denver, Colorado, 80218, United States

  • Derriford Hospital

    RECRUITING

    Plymouth, United Kingdom

  • Florida Cancer Specialists

    RECRUITING

    Sarasota, Florida, 34232, United States

  • Hôpital Saint-Louis

    RECRUITING

    Paris, Paris, 75610, France

  • Imperial College / Clinical Trials Unit, Hammersmith Hospital

    RECRUITING

    London, United Kingdom

  • Institut Gustave Roussy

    RECRUITING

    Villejuif, France

  • Institut Paoli Calmettes

    RECRUITING

    Marseille, France

  • Memorial Sloan Kettering

    RECRUITING

    New York, New York, 10065, United States

  • Nottingham City Hospital

    RECRUITING

    Nottingham, United Kingdom

  • The Centre Léon Bérard

    RECRUITING

    Lyon, France

  • The Christie

    RECRUITING

    Manchester, United Kingdom

  • The Royal Marsden

    RECRUITING

    Sutton, United Kingdom

  • University Hospitals of Leicester NHS Trust

    RECRUITING

    Leicester, United Kingdom

More trials for these conditions

Other studies related to the condition(s) this trial covers.