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New drug combo shows promise for rare lymphoma in Real-World study

NCT ID NCT07624838

Recruiting now Disease control Sponsor: Grupo Español de Linfomas y Transplante Autólogo de Médula Ósea Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This observational study tracks 100 adults in Spain with CD30-positive peripheral T-cell lymphoma who received brentuximab vedotin plus CHP as their first treatment. Researchers will review medical records to see how long patients live without their cancer getting worse, how well the treatment shrinks tumors, and what side effects occur. The goal is to understand how this drug combination works in everyday medical practice.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
brentuximab vedotin plus CHP (a combination of a targeted antibody drug and three chemotherapy drugs)
What this could lead to
If this study confirms good results, it could support using this drug combination as a standard first-line treatment for this rare type of lymphoma.
What could go wrong
This is an observational study, not a controlled trial, so results may be less reliable. Side effects like nerve damage and low white blood cell counts are possible.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

anaplastic large cell lymphoma angioimmunoblastic T-cell lymphoma enteropathy-associated T-cell lymphoma hepatosplenic T-cell lymphoma mature T-cell and NK-cell non-Hodgkin lymphoma peripheral T-cell lymphoma, not otherwise specified

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CD30-POSITIVE PERIPHERAL T-CELL LYMPHOMA

Contacts and locations

Locations

  • Clínica Universidad de Navarra

    RECRUITING

    Pamplona, Navarre, 31008, Spain

  • Hospital Clínic de Barcelona

    RECRUITING

    Barcelona, Barcelona, 08036, Spain

  • Hospital Francesc de Borja

    RECRUITING

    Gandia, Valencia, 46702, Spain

  • Hospital General Universitario Santa Lucía

    RECRUITING

    Cartagena, Murcia, 30202, Spain

  • Hospital General de Segovia

    RECRUITING

    Segovia, Segovia, 40002, Spain

  • Hospital Moisès Broggi

    RECRUITING

    Sant Joan Despí, Barcelona, 08970, Spain

  • Hospital Universitari Son Espases

    RECRUITING

    Palma de Mallorca, Balearic Islands, 07120, Spain

  • Hospital Universitari Son Llàtzer

    RECRUITING

    Palma de Mallorca, Balearic Islands, 07008, Spain

  • Hospital Universitari Vall d'Hebron

    RECRUITING

    Barcelona, Barcelona, 08035, Spain

  • Hospital Universitari i Politècnic La Fe

    RECRUITING

    Valencia, Valencia, 46026, Spain

  • Hospital Universitario 12 de Octubre

    RECRUITING

    Madrid, Madrid, 28041, Spain

  • Hospital Universitario A Coruña

    RECRUITING

    A Coruña, A Coruña, 15006, Spain

  • Hospital Universitario Central de Asturias

    RECRUITING

    Oviedo, Principality of Asturias, 33011, Spain

  • Hospital Universitario Doctor Negrín

    RECRUITING

    Las Palmas de Gran Canaria, Las Palmas, 35010, Spain

  • Hospital Universitario Donostia

    RECRUITING

    San Sebastián, Gipuzkoa, 20014, Spain

  • Hospital Universitario Gregorio Marañón

    RECRUITING

    Madrid, Madrid, 28007, Spain

  • Hospital Universitario Juan Ramón Jiménez

    RECRUITING

    Huelva, Huelva, 21005, Spain

  • Hospital Universitario Marqués de Valdecilla

    RECRUITING

    Santander, Cantabria, 39008, Spain

  • Hospital Universitario Morales Meseguer

    RECRUITING

    Murcia, Murcia, 30008, Spain

  • Hospital Universitario Príncipe de Asturias

    RECRUITING

    Alcalá de Henares, Madrid, 28805, Spain

  • Hospital Universitario Ramón y Cajal

    RECRUITING

    Madrid, Madrid, 28034, Spain

  • Hospital Universitario Rey Juan Carlos

    RECRUITING

    Móstoles, Madrid, 28933, Spain

  • Hospital Universitario San Agustín

    RECRUITING

    Avilés, Principality of Asturias, 33401, Spain

  • Hospital Universitario Severo Ochoa

    RECRUITING

    Leganés, Madrid, 28911, Spain

  • Hospital Universitario Virgen Macarena

    RECRUITING

    Seville, Sevilla, 41009, Spain

  • Hospital Universitario de Canarias

    RECRUITING

    San Cristóbal de La Laguna, Santa Cruz de Tenerife, 38320, Spain

  • Hospital Universitario de Jerez

    RECRUITING

    Jerez de la Frontera, Cádiz, 11407, Spain

  • Hospital Universitario de La Princesa

    RECRUITING

    Madrid, Madrid, 28006, Spain

  • Hospital Universitario de Salamanca

    RECRUITING

    Salamanca, Salamanca, 37007, Spain

  • Hospital de la Santa Creu i Sant Pau

    RECRUITING

    Barcelona, Barcelona, 08041, Spain

  • Hospital del Mar

    RECRUITING

    Barcelona, Barcelona, 08003, Spain

  • Hospital del Sureste

    RECRUITING

    Arganda, Madrid, 28500, Spain

  • Hospital Álvaro Cunqueiro

    RECRUITING

    Vigo, Pontevedra, 36213, Spain

  • ICO Girona - Hospital Dr. Josep Trueta

    RECRUITING

    Girona, Girona, 17007, Spain

  • ICO Hospital Duran i Reynals

    RECRUITING

    L'Hospitalet de Llobregat, Barcelona, 08908, Spain

  • ICO Hospital Germans Trias i Pujol

    RECRUITING

    Badalona, Barcelona, 08916, Spain

  • ICO Hospital Universitari Joan XXIII

    RECRUITING

    Tarragona, Tarragona, 43005, Spain

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