New shot could ease painful skin condition

NCT ID NCT06411379

Completed Disease control Sponsor: MoonLake Immunotherapeutics AG Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested a drug called sonelokimab in 418 adults with moderate to severe hidradenitis suppurativa, a skin condition that causes painful lumps and abscesses. Participants received either the drug or a placebo injection for 16 weeks. The goal was to see if sonelokimab reduces the number of inflamed lumps and draining tunnels by at least 75%.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Sonelokimab (a drug injected under the skin)

What this could lead to

If it works, this could provide a new treatment option for people with moderate to severe hidradenitis suppurativa, reducing painful lumps and abscesses.

What could go wrong

This is a completed Phase 3 trial, but results are not yet public. The drug may not work better than placebo, and side effects are possible. It is not a cure, and ongoing treatment may be needed.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

hidradenitis hidradenitis suppurativa skin disease caused by bacterial infection skin disorder Suppuration sweat gland disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

HIDRADENITIS SUPPURATIVA

Contacts and locations

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Locations

Clinical SIte

Brest, 29200, France
Clinical Site

Birmingham, Alabama, 35244, United States
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North Little Rock, Arkansas, 72117, United States
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Fountain Valley, California, 92708, United States
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Santa Monica, California, 90404, United States
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Aventura, Florida, 33180, United States
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Hialeah, Florida, 33012, United States
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Miami, Florida, 33136, United States
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Ocala, Florida, 34470, United States
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Tampa, Florida, 33613, United States
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Skokie, Illinois, 60077, United States
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Plainfield, Indiana, 46168, United States
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Murray, Kentucky, 42071, United States
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Baton Rouge, Louisiana, 70809, United States
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Baltimore, Maryland, 21287, United States
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Ann Arbor, Michigan, 48109-5314, United States
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Canton, Michigan, 48187, United States
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Clarkston, Michigan, 48346, United States
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Waterford, Michigan, 48328, United States
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New Brighton, Minnesota, 55112, United States
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Omaha, Nebraska, 68144, United States
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Las Vegas, Nevada, 89145, United States
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New York, New York, 10003, United States
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Fargo, North Dakota, 58103, United States
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Columbus, Ohio, 43213, United States
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Murfreesboro, Tennessee, 37130, United States
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Dallas, Texas, 75390-8565, United States
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Plano, Texas, 75025, United States
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San Antonio, Texas, 78213, United States
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Morgantown, West Virginia, 26505, United States
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Milwaukee, Wisconsin, 53226, United States
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Ghent, 9000, Belgium
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Leuven, 3000, Belgium
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Liège, 4000, Belgium
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Woluwe-Saint-Lambert, 1200, Belgium
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Sofia, 1431, Bulgaria
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Sofia, 1463, Bulgaria
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Sofia, 1510, Bulgaria
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Sofia, 1606, Bulgaria
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Stara Zagora, 6003, Bulgaria
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Calgary, Alberta, T3E 0B2, Canada
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Edmonton, Alberta, T6G 1C3, Canada
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Guelph, Ontario, N1L 0B7, Canada
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Peterborough, Ontario, K9J 5K2, Canada
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Richmond Hill, Ontario, L4B 1A5, Canada
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Toronto, Ontario, M4E 1R7, Canada
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Windsor, Ontario, N8W 1E6, Canada
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Saskatoon, Saskatchewan, S7K 2C1, Canada
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Ostrava, 708 52, Czechia
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Prague, 110 00, Czechia
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Prague, 15006, Czechia
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Antony, 92160, France
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Besançon, 25030, France
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Dijon, 21000, France
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Le Mans, 72037, France
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Lyon, 69003, France
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Montpellier, 34295, France
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Rouen, 76031, France
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Saint-Mandé, 94160, France
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Saint-Priest-en-Jarez, 42270, France
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Toulouse, 31400, France
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Augsburg, 86179, Germany
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Bad Bentheim, 48455, Germany
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Berlin, 10117, Germany
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Bielefeld, 33647, Germany
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Bochum, 44791, Germany
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Bramsche, 49565, Germany
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Darmstadt, 64283, Germany
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Dresden, 01307, Germany
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Gera, 07548, Germany
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Hamburg, 20246, Germany
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Kiel, 24105, Germany
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Lübeck, 23538, Germany
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Würzburg, 97080, Germany
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Dublin, D04 T6F4, Ireland
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Rotterdam, 3015 GD, Netherlands
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Chorzów, 41-500, Poland
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Katowice, 40-611, Poland
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Kielce, 25-316, Poland
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Olsztyn, 10-229, Poland
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Poznan, 61-731, Poland
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Szczecin, 70-332, Poland
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Warsaw, 02-953, Poland
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Wroclaw, 50566, Poland
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Trnava, 91702, Slovakia
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Alcorcón, 28922, Spain
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Alicante, 03010, Spain
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Badalona, 08916, Spain
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Barcelona, 08003, Spain
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Barcelona, 08036, Spain
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Barcelona, 08041, Spain
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Cadiz, 11009, Spain
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Córdoba, 14004, Spain
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Granada, 18012, Spain
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Granada, 18014, Spain
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Granollers, 08402, Spain
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Madrid, 28006, Spain
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Madrid, 28007, Spain
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Madrid, 28041, Spain
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Madrid, 28046, Spain
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Manises, 46940, Spain
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Málaga, 29010, Spain
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Santiago de Compostela, 15706, Spain
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Seville, 41009, Spain
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Valencia, 46014, Spain
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Valencia, 46026, Spain