Could a simple salt solution help the brain after severe injury?

NCT ID NCT06701760

Not yet recruiting Disease control Sponsor: University of California, Los Angeles Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether a sodium lactate infusion is safe for people with severe traumatic brain injury in the ICU. Researchers will monitor side effects and survival in 264 adults. The goal is to see if this approach is safe enough to study further.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: sodium lactate
What this could lead to: If safe, this could point toward a new way to manage severe traumatic brain injury in the ICU.
What could go wrong: This is an early safety trial, so it may not show any benefit. The treatment is only for a specific group of patients with severe injuries.

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Conditions

The condition(s) this trial relates to.

Brain Injuries, Traumatic Coma traumatic brain injury

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

TRAUMATIC BRAIN INJURY

More trials for these conditions

Other studies related to the condition(s) this trial covers.