Can smell training rewire the brain and immune system?
NCT ID NCT07681973
First seen Jul 02, 2026 · Last updated Jul 02, 2026
Summary
This study looks at people with smell loss caused by chronic rhinosinusitis. Participants will undergo a 3-month smell training program. Researchers will measure changes in smell function, mental health, and immune markers in blood and tissue samples. The goal is to understand the links between smell loss, cognition, and the immune system to help develop future treatments.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- smell training
- What this could lead to
- If successful, this study could identify molecules linked to smell loss, pointing toward future treatments.
- What could go wrong
- This is a small, early-stage study focused on understanding mechanisms, not testing a treatment. Results may not lead directly to therapies.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
The Cleveland Clinic
RECRUITINGCleveland, Ohio, 44195, United States
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