Can a simple test predict when smell returns?

NCT ID NCT06892704

First seen Jul 16, 2026 · Last updated Jul 17, 2026 · Updated 1 time

Summary

This study follows 30 people with chronic sinusitis and nasal polyps who are starting dupilumab, a medication that can help restore smell. Researchers want to see if the degree of nasal blockage or specific electrical signals from the brain can predict who will regain their sense of smell. Participants will be monitored for six months with smell tests and nasal assessments.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
dupilumab
What this could lead to
If successful, this could help doctors predict which patients with nasal polyps and smell loss will regain their sense of smell with dupilumab treatment.
What could go wrong
This is a small observational study, not a treatment trial. It aims to find predictors, not prove that dupilumab works for smell loss.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Northwestern University Feinberg School of Medicine

    RECRUITING

    Chicago, Illinois, 60611, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

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