New hope for advanced cancer? SLV-324 enters first human trial

NCT ID NCT07108114

Recruiting now Disease control Sponsor: Solve Therapeutics Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This early-stage trial tests a new drug called SLV-324 in about 70 people with metastatic solid tumors that have worsened after standard treatments. The main goal is to find a safe dose and check for side effects. Researchers will also look at how the drug moves through the body and whether it shows any signs of shrinking tumors.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: SLV-324 (intravenous infusion)
What this could lead to: If successful, this could point toward a new treatment option for people with advanced solid tumors that have not responded to other therapies.
What could go wrong: This is a very early Phase 1 study with only 70 participants, so the main goal is safety, not proof of effectiveness. Many drugs fail at this stage, and side effects are unknown.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

metastatic malignant neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

METASTATIC SOLID TUMORS

Contacts and locations

Locations

Fox Chase Cancer Center
RECRUITING

Philadelphia, Pennsylvania, 19111, United States
Hoag Memorial Hospital Presbyterian
RECRUITING

Newport Beach, California, 92663, United States
MD Anderson Cancer Center
RECRUITING

Houston, Texas, 77030, United States
Mays Cancer Center; University of Texas Health San Antonio
RECRUITING

Houston, Texas, 78229, United States
University Hospitals Cleveland Medical Center
RECRUITING

Cleveland, Ohio, 44106, United States
University of Washington / Fred Hutchinson Cancer Center
RECRUITING

Seattle, Washington, 98109, United States
Washington University
RECRUITING

St Louis, Missouri, 63110, United States

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