Brain-Boosting sounds during sleep tested for schizophrenia

NCT ID NCT05956951

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looks at brain activity during sleep in people with early-course schizophrenia compared to healthy individuals. Researchers will play soft tones during deep sleep using a wearable headband to see if it can strengthen sleep-related brain waves and improve memory. The goal is to understand sleep differences and explore a potential way to boost cognitive function without medication.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Closed-loop auditory stimulation via wearable EEG headband
What this could lead to
If successful, this could point toward a non-drug method to improve memory and thinking in people with early schizophrenia.
What could go wrong
This is an early-stage study focused on measuring brain activity, not a treatment trial. The sound stimulation may not produce meaningful cognitive benefits, and results may not apply to all patients.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • University of Pittsburgh

    RECRUITING

    Pittsburgh, Pennsylvania, 15213, United States

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