New hope for toddlers with brain tumors: tailored therapy aims to boost survival and protect young minds

NCT ID NCT05535166

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests a personalized treatment plan for children under 5 with a type of brain cancer called medulloblastoma. Doctors use the tumor's genetic makeup and the child's age to choose the best mix of chemotherapy and, if needed, radiation. The goal is to improve survival while reducing long-term harm to thinking and learning. About 130 children will take part across multiple countries.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • C.S. MOTT Children's Hospital, University of Michigan

    RECRUITING

    Ann Arbor, Michigan, 48109, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Children's Hospital and Clinics of Minnesota

    RECRUITING

    Minneapolis, Minnesota, 55404, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Cook Children's Medical Center

    RECRUITING

    Fort Worth, Texas, 76104, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Lucille Packard Children's Hospital Stanford

    RECRUITING

    Palo Alto, California, 94304, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Orlando Health Arnold Palmer Hospital for Children

    RECRUITING

    Orlando, Florida, 32806, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Primary Children's Hospital

    RECRUITING

    Salt Lake City, Utah, 84113, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • St. Joseph's Children's Hospital

    RECRUITING

    Tampa, Florida, 33607, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • St. Jude Children's Research Hospital

    RECRUITING

    Memphis, Tennessee, 38105, United States

    Contact

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Texas Children's Hospital

    RECRUITING

    Houston, Texas, 77477, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • UT Southwestern Medical Center/Harold C Simmons Comprehensive Cancer Center

    RECRUITING

    Dallas, Texas, 75235, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

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