First-Ever trial aims to stop seizures before they start in rare genetic disorder

NCT ID NCT05104983

Summary

This study is testing if a drug called sirolimus, given early in life, can prevent or delay the onset of seizures in infants diagnosed with Tuberous Sclerosis Complex (TSC). It will enroll 64 infants under 7 months old who have TSC but have not yet had seizures. The goal is to see if this targeted treatment can improve long-term brain development and quality of life by stopping a major symptom before it begins.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Boston Children's Hospital

    RECRUITING

    Boston, Massachusetts, 02115, United States

    Contact

    Contact

  • Children's Hospital Colorado

    RECRUITING

    Aurora, Colorado, 80045, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Cincinnati Children's Hospital Medical Center

    RECRUITING

    Cincinnati, Ohio, 45229, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Lurie Children's Hospital of Chicago

    RECRUITING

    Chicago, Illinois, 60611, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Seattle Children's Hospital

    RECRUITING

    Seattle, Washington, 98105, United States

    Contact

    Contact

  • Stanford University

    RECRUITING

    Palo Alto, California, 94304, United States

    Contact

    Contact Email: •••••@•••••

  • University of Alabama at Birmingham

    RECRUITING

    Birmingham, Alabama, 35294, United States

    Contact

    Contact

  • University of California at Los Angeles

    RECRUITING

    Los Angeles, California, 90095, United States

    Contact

    Contact

  • University of North Carolina at Chapel Hill

    ACTIVE_NOT_RECRUITING

    Chapel Hill, North Carolina, 27510, United States

  • University of Texas HSC at Houston

    RECRUITING

    Houston, Texas, 77030, United States

    Contact

    Contact

  • Washington University -- St. Louis

    RECRUITING

    St Louis, Missouri, 63110, United States

    Contact

    Contact

Conditions

Explore the condition pages connected to this study.