Can a common drug boost brain blood flow in Alzheimer's gene carriers?
NCT ID NCT05386914
First seen Mar 17, 2026 · Last updated Jun 07, 2026 · Updated 17 times
Summary
This early-stage study looks at whether sirolimus, an FDA-approved drug, can increase blood flow to the brain in healthy adults aged 45-65. Some participants carry a gene (APOE4) that raises Alzheimer's risk, while others do not. The goal is to understand how the drug affects brain and lung blood flow, not to treat or cure Alzheimer's.
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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Locations
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University of Missouri-Columbia
Columbia, Missouri, 65212, United States
Conditions
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