Can a common drug boost brain blood flow and fight Alzheimer's risk?

NCT ID NCT05386914

First seen Mar 17, 2026 · Last updated Apr 29, 2026 · Updated 7 times

Summary

This early-stage study looks at whether sirolimus, an FDA-approved drug, can improve blood flow to the brain in healthy adults aged 45-65, especially those with a genetic risk for Alzheimer's disease. Researchers use MRI scans to measure changes. The goal is to understand how the drug affects brain circulation and its link to lung function, not to treat or cure Alzheimer's.

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Contacts and locations

Locations

  • University of Missouri-Columbia

    Columbia, Missouri, 65212, United States

Conditions

Explore the condition pages connected to this study.