New hope for ruptured liver cancer: drug combo aims to stop recurrence

NCT ID NCT07331883

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether two drugs, sintilimab and bevacizumab, given after surgery can prevent cancer from coming back in people with ruptured liver cancer. About 35 participants will receive the combination every three weeks. The goal is to see if this approach is safe and improves how long people live without their cancer returning.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

sintilimab and bevacizumab biosimilar

What this could lead to

If this works, it could provide a new treatment option to lower the risk of cancer returning after surgery for ruptured liver cancer.

What could go wrong

This is a small, early-phase study with only 35 participants and no comparison group. The combination may cause side effects and might not prove effective in larger trials.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

hepatocellular carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Huashan Hospital, Fudan University

    RECRUITING

    Shanghai, Shanghai Municipality, 200031, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Ruijin Hospital, Shanghai Jiao Tong University School of Medicine

    RECRUITING

    Shanghai, Shanghai Municipality, 200025, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Sanming First Hospital

    NOT_YET_RECRUITING

    Sanming, Fujian, 365000, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • The Third Bethune Hospital of Jilin University

    RECRUITING

    Changchun, Jilin, 130033, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact