New gel could replace hormone cream for menopause discomfort
NCT ID NCT05672901
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study compares a silicone gel (StrataMGT) to standard estrogen cream for treating genitourinary syndrome of menopause, which causes vaginal dryness and irritation. About 100 postmenopausal women will use one of the treatments for three months. Researchers will check if the gel works as well as estrogen at improving quality of life.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
silicone gel (StrataMGT)
What this could lead to
If it works, this could offer a hormone-free option for managing menopause symptoms like dryness and irritation.
What could go wrong
This is a small early-stage trial with only 100 participants, so results may not apply to everyone. The gel may not work as well as estrogen cream.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Abba Medical Group
RECRUITINGMiami, Florida, 33176, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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One Health Research Clinic
RECRUITINGJohns Creek, Georgia, 30097, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Orange Coast Women's Medical Group
RECRUITINGLaguna Hills, California, 92653, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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