New gel could replace hormone cream for menopause discomfort

NCT ID NCT05672901

Recruiting now Symptom relief Sponsor: Stratpharma AG Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study compares a silicone gel (StrataMGT) to standard estrogen cream for treating genitourinary syndrome of menopause, which causes vaginal dryness and irritation. About 100 postmenopausal women will use one of the treatments for three months. Researchers will check if the gel works as well as estrogen at improving quality of life.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: silicone gel (StrataMGT)
What this could lead to: If it works, this could offer a hormone-free option for managing menopause symptoms like dryness and irritation.
What could go wrong: This is a small early-stage trial with only 100 participants, so results may not apply to everyone. The gel may not work as well as estrogen cream.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

postmenopausal atrophic vaginitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

GENITOURINARY SYNDROME OF MENOPAUSE

Contacts and locations

Locations

Abba Medical Group
RECRUITING

Miami, Florida, 33176, United States
One Health Research Clinic
RECRUITING

Johns Creek, Georgia, 30097, United States
Orange Coast Women's Medical Group
RECRUITING

Laguna Hills, California, 92653, United States

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