Scientists probe hidden triggers of sickle cell pain crises

NCT ID NCT05646888

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looks at how platelets and inflammation work together during painful crises in adults with sickle cell disease. Researchers will take blood samples from 25 patients hospitalized for a crisis to analyze these processes. The goal is to better understand the disease, not to test a new treatment.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to

If successful, this research could reveal new targets for treatments that reduce painful crises in sickle cell disease.

What could go wrong

This is a small, early observational study (25 participants) that only collects blood samples. It is not testing a treatment, so it may not lead directly to new therapies.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

sickle cell disease Thromboinflammation Vaso-Occlusive Crises

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • IUCT-Oncopole University Hospital

    Toulouse, 31500, France