Shoulder block study checks for breathing side effects

NCT ID NCT04209504

Recruiting now Knowledge-focused Sponsor: Duke University Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study observes 60 adults having shoulder surgery to see how often a common nerve block (interscalene brachial plexus block) causes temporary paralysis of the diaphragm, the main breathing muscle. Participants are split into three groups receiving different types of local anesthetics. Researchers use ultrasound to check diaphragm movement right after surgery and for three days afterward. The goal is to understand which block method is safest for breathing.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Ropivacaine and bupivacaine (local anesthetics)
What this could lead to: If successful, this could help doctors choose the safest nerve block method for shoulder surgery, reducing breathing complications.
What could go wrong: This is a small, early observational study, not a treatment trial. Results may not apply to all patients, and the nerve block itself carries rare risks like nerve damage or allergic reaction.

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Conditions

The condition(s) this trial relates to.

osteoarthritis Rotator Cuff Injuries rotator cuff syndrome Shoulder Injuries Shoulder Pain

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ROTATOR CUFF ARTHROPATHY OF LEFT SHOULDER ROTATOR CUFF ARTHROPATHY OF RIGHT SHOULDER ROTATOR CUFF INJURIES ROTATOR CUFF REPAIR ROTATOR CUFF TEARS SHOULDER ARTHRITIS SHOULDER DISEASE SHOULDER INJURIES SHOULDER PAIN SHOULDER SURGERY

Contacts and locations

Locations

Duke University Hospital
RECRUITING

Durham, North Carolina, 27710, United States

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