Can patients get up sooner after vein procedures without more bleeding?

NCT ID NCT07807787

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First seen Sep 08, 2026 · Last updated Sep 09, 2026 · Updated 1 time

Summary

This trial compares three bed-rest strategies after procedures that use the femoral vein in the groin. Some patients rest for 2 hours, others for 4 or 8 hours. Researchers want to see if shorter rest is just as safe, meaning no more bleeding or bruising at the puncture site, and whether it improves comfort, reduces back pain and anxiety, and lets patients move sooner. Adults having certain vein procedures will be randomly assigned to one of the three rest periods and monitored for complications.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Behavioral intervention: shorter postprocedural immobilization and bed rest (2 or 4 hours) compared with standard 8 hours
What this could lead to
If shorter rest is safe, patients could recover faster with less back pain and anxiety after vein procedures.
What could go wrong
Shorter rest might raise bleeding risk at the puncture site, and the trial's results may not apply to all patients or procedures.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 1,550 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Sep 2026

An estimate. Start dates often move.

Expected to finish

Oct 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1. Age ≥18 years. 2. No clinically significant neurological or cognitive impairment, and no pre-existing condition causing substantial limitation of lower-extremity mobility before the procedure. 3. Undergoing at least one of the following peripheral venous interventional procedures via femoral venous access, with postprocedural hemostasis achieved by manual compression: Lower-extremity venography alone; Inferior vena cava filter placement; Iliac vein stent placement; Endovascular thrombus removal for lower-extremity deep vein thrombosis; Other peripheral venous interventions using a 5-12 F sheath, including balloon angioplasty alone, pelvic vein embolization, or renal vein stent placement. 4. Able to understand the purpose and procedures of the study, provide written informed consent, and comply with the study procedures and follow-up. Exclusion Criteria: 1. Concomitant ipsilateral femoral arterial access during the index procedure or inadvertent percutaneous puncture of the femoral artery. 2. Visible access-site hematoma, persistent bleeding or oozing, pseudoaneurysm, or arteriovenous fistula occurring during femoral venous puncture or after sheath removal before randomization. 3. Requirement for additional non-protocol anticoagulation after the procedure, or any foreseeable condition preventing adherence to the assigned immobilization and bed-rest schedule or completion of the scheduled assessments. 4. Planned repeat puncture in the femoral region during the observation period or requirement for continued placement of a large-bore vascular sheath. 5. Use of thrombolytic agents during the procedure or requirement for continued intravenous thrombolytic therapy after the procedure. 6. Severe obesity or other conditions that make effective manual compression of the femoral access site difficult. 7. Hemodynamic instability identified before randomization. 8. Severe cardiac, hepatic, or renal insufficiency. Severe hepatic insufficiency is defined as alanine aminotransferase (ALT) \>2 times the upper limit of normal or aspartate aminotransferase (AST) \>2 times the upper limit of normal. Severe renal insufficiency is defined as serum creatinine \>1.5 times the upper limit of normal or estimated glomerular filtration rate (eGFR) \<45 mL/min/1.73 m². 9. Clinically significant coagulation abnormality, including a platelet count \<100 × 10\^9/L. 10. General anesthesia used during the index procedure.

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