Could a 5-Day radiation blast ease suffering in kids with incurable brain cancer?

NCT ID NCT07147179

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This pilot trial is testing a shorter, 5-day course of radiation for children and young adults (up to age 21) with incurable central nervous system cancers. The main goal is to see if this approach is safe and does not cause severe side effects. Researchers will also track quality of life. Only 15 participants will be enrolled, making this an early safety study.

What this could mean

Our plain-language read of the trial. This is informational only โ€” not medical advice or a prediction.

Active substance
Radiation therapy (short course, 20 Gray in 5 fractions)
What this could lead to
If successful, this could offer a quicker, less burdensome radiation option for children with incurable brain or spinal cancers, potentially improving their quality of life.
What could go wrong
This is a very small pilot study (15 participants) with no control group, so results may not apply broadly. The main risk is that the shorter radiation course could cause serious side effects.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • University of Pennsylvania

    RECRUITING

    Philadelphia, Pennsylvania, 19104, United States

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Other studies related to the condition(s) this trial covers.