New combo shrinks rectal tumors before surgery

NCT ID NCT04417699

Completed Disease control Sponsor: Providence Health & Services Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested a shorter radiation course combined with TASOX chemotherapy in 13 people with stage II/III rectal cancer before surgery. The goal was to shrink tumors and make surgery more effective. Results showed the treatment was safe and helped reduce cancer stage, but ongoing monitoring or additional treatment may still be needed.

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Conditions

The condition(s) this trial relates to.

rectal cancer rectal neoplasm rectum adenocarcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

RECTAL CANCER

Contacts and locations

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Locations

Columbia University Irving Medical Center/NYPH

New York, New York, 10032, United States
Providence Portland Medical Center

Portland, Oregon, 97213, United States
University of California, Irvine

Orange, California, 92868, United States
Virginia Mason Medical Center

Seattle, Washington, 98101, United States