Sound waves smash artery calcium in new leg treatment trial

NCT ID NCT05058456

Completed Disease control Sponsor: Shockwave Medical, Inc. Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Aug 04, 2026 · Updated 2 times

Summary

This study tested a new device that uses sound waves to break up calcium deposits in leg arteries of people with peripheral artery disease. Thirty-five participants received the treatment to see if it was safe and could open blocked arteries. The goal was to improve blood flow without causing serious complications.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Shockwave Medical Mini S Peripheral IVL Catheter (a device that delivers sound waves to break up calcium deposits in arteries)
What this could lead to: If successful, this device could offer a new way to treat hardened leg arteries without major surgery, potentially improving blood flow and reducing symptoms like pain or poor wound healing.
What could go wrong: This is a small, early feasibility study with only 35 participants and no comparison group, so results may not apply to everyone. Risks include artery damage, blood clots, or the need for additional procedures.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

peripheral arterial disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

PERIPHERAL ARTERIAL DISEASE

Contacts and locations

Locations

Auckland City Hospital

Auckland, New Zealand
Royal Perth Hospital

Perth, Australia
Sir Charles Gairdner Hospital

Nedlands, Perth, Australia
Waikato Hospital

Hamilton, New Zealand

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