Could shock waves boost botox for Stroke-Related foot stiffness?

NCT ID NCT07758322

First seen Aug 11, 2026 · Last updated Aug 12, 2026 · Updated 1 time

Summary

This trial investigates whether adding focused shock wave therapy to standard Botox injections can better ease foot stiffness and improve walking in people with post-stroke spastic equinovarus foot. Participants are randomly assigned to receive Botox alone, shock waves just before Botox, or shock waves two weeks after. The study measures changes in spasticity, ankle movement, muscle strength, and walking ability over a year to see if the timing of shock wave therapy makes a difference.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Botulinum toxin type A (Botox) combined with focused extracorporeal shock wave therapy
What this could lead to
If adding shock wave therapy improves outcomes, it could establish a better standard of care for post-stroke foot spasticity, enhancing mobility and quality of life.
What could go wrong
This is a small, early-stage trial, and the optimal timing of shock wave therapy remains uncertain. Results may not generalize, and individual responses to Botox and shock waves can vary.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Muscle Spasticity stroke disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Hospital Clinico San Carlos

    Madrid, Madrid, 28040, Spain

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