Promising new shingles vaccine enters human trials

NCT ID NCT06932523

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests a new recombinant shingles vaccine in healthy adults aged 40 and above. Researchers will give two doses and monitor for side effects and immune response. The trial involves 645 participants and compares the new vaccine to an existing one (Shingrix) and placebo.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
recombinant herpes zoster vaccine (CHO cells)
What this could lead to
If successful, this could provide a new option to prevent shingles in adults 40 and older.
What could go wrong
This is an early-phase trial (phase 1/2) with 645 participants, so safety and effectiveness are not yet proven. The vaccine may cause side effects or fail to generate strong immunity.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Hubei Provincial Center for Disease Control and Prevention

    RECRUITING

    Wuhan, Hubei, China

More trials for these conditions

Other studies related to the condition(s) this trial covers.