Can the shingles vaccine protect those with autoimmune conditions?
NCT ID NCT07280741
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study is testing whether the shingles vaccine (RZV) works and is safe for adults with autoimmune rheumatic diseases like rheumatoid arthritis or lupus who are taking immune-suppressing drugs. Two hundred participants will receive two doses of the vaccine. Researchers will measure antibody levels and track shingles cases to see if the vaccine provides protection.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Recombinant Zoster Vaccine (Shingrix)
What this could lead to
If successful, this could show that the shingles vaccine is effective and safe for people with autoimmune rheumatic diseases on immunomodulators, helping prevent a painful condition.
What could go wrong
This is a phase 4 trial with 200 participants, so results may not apply to everyone. The vaccine might be less effective in people on certain immune-suppressing drugs, and side effects are possible.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Hospital das Clínicas
RECRUITINGSão Paulo, São Paulo, 05403-010, Brazil
Contact Phone: •••-•••-•••• Email: •••••@•••••