Can an ancient herb ease menopause symptoms? new study investigates
NCT ID NCT07441109
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 2 times
Summary
This study tests whether a daily capsule of shatavari (Asparagus racemosus) root extract can help women aged 40-45 with perimenopause symptoms like hot flashes, mood swings, and sleep trouble. Sixty women will take either the extract or a placebo for 12 weeks. Researchers will track changes in symptom severity and quality of life using standard questionnaires.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Shatavari (Asparagus racemosus) root extract
- What this could lead to
- If it works, this could offer a natural option to reduce common perimenopause symptoms like hot flashes and sleep problems.
- What could go wrong
- This is a small, early-stage trial with only 60 women, so results may not apply to everyone. The supplement may not work better than a placebo.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 60 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Mar 2026
An estimate. Start dates often move.
- Expected to finish
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Jun 2026
An estimate. End dates often move.
- Lead sponsor
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A research network
The lead sponsor is a research network or cooperative group.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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40 to 45 years
- Sex
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Female participants only
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: 1. Menopausal women aged \>40 to 45 years with intact uterus and ovaries. 2. Participants who complained of irregular menstrual cycle in the past 12 months, with a forward or postpone of a cycle more 7 days. At least 2 cycles were missing during the past 12 months or reported menopause for at least 60 days. 3. Females with complaints of at least two of the menopausal symptoms, e.g., hot flashes, night sweats, mood swings, sleep disturbance, breast tenderness 4. Body mass index 18-35 kg/m2 5. Subject who has given written informed consent to participate in the study and understand the nature of the study. 6. Able to read and write in English or any other vernacular language. 7. No plan to commence new treatments over the study period. 8. Must have the ability and willingness to si Exclusion Criteria: 1. Participants taking any form of herbal extract in the last 3 months before study entry. 2. Participants who are on hormone replacement therapy (HRT) for more than 3 months. 3. Participants who are pregnant. 4. Participants with present active medical, surgical, and gynaecological problems. 5. Participants with a history of alcohol, tobacco dependence, or any substance abuse. 6. Participants who had undergone bilateral ovariectomy 7. Participants with history of breast or cervical carcinoma 8. Participants who taking medication that affect bone metabolism, including glucocorticoid, anticonvulsant, and methotrexate. 9. Participants with clinically relevant cardiovascular, gastrointestinal, hepatic, neurologic, endocrine, haematologic or other major systemic diseases making implementation of the protocol or other interpretation of the study result difficult. 10. Participants with mental condition rendering the subject unable to understand the nature, scope, and possible consequences of the study. 11. Participants with evidence of demonstrated inability to follow study protocols or attend follow-up visits, including poor compliance. 12. Participants with demonstrated inability to follow study protocols or attend follow-up visit 13. Participants with inability to attend follow-up visit 14. Participants with any other medical condition (for example uncontrolled infection) that may, in the opinion of the Investigator, interfere with the study objective. 15. Patients who had participated in other clinical trials during the previous 3 months. 16. Patients who have any clinical condition, according to the investigator, who does not allow safe fulfilment of clinical trial protocol.
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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San Francisco Research Institute
San Francisco, California, 94132, United States
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