Could a common diabetes drug shield heart transplant patients from kidney damage?

NCT ID NCT06625073

First seen Jan 25, 2026 · Last updated Apr 25, 2026 · Updated 10 times

Summary

This study tests whether empagliflozin, a drug used for diabetes, can protect the kidneys and heart in people who have received a heart transplant. About 200 veterans who had a heart transplant at least three months ago will take either the drug or a placebo for one year. The goal is to see if the drug helps prevent kidney and heart problems that often occur due to the lifelong anti-rejection medicines required after transplant.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Hunter Holmes McGuire VA Medical Center, Richmond, VA

    NOT_YET_RECRUITING

    Richmond, Virginia, 23249-0001, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Michael E. DeBakey VA Medical Center, Houston, TX

    NOT_YET_RECRUITING

    Houston, Texas, 77030-4211, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Tennessee Valley Healthcare System Nashville Campus, Nashville, TN

    NOT_YET_RECRUITING

    Nashville, Tennessee, 37212-2637, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • VA Palo Alto Health Care System, Palo Alto, CA

    NOT_YET_RECRUITING

    Palo Alto, California, 94304-1207, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • VA Salt Lake City Health Care System, Salt Lake City, UT

    RECRUITING

    Salt Lake City, Utah, 84148-0001, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • William S. Middleton Memorial Veterans Hospital, Madison, WI

    NOT_YET_RECRUITING

    Madison, Wisconsin, 53705-2254, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

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