Could a drug for schizophrenia work differently in men and women?
NCT ID NCT07122895
First seen Jun 26, 2026 · Last updated Jun 26, 2026
Summary
This study is testing whether an NMDA-enhancing drug can improve negative symptoms of schizophrenia (like lack of motivation or social withdrawal) and if it works better in men or women. 90 people with stable schizophrenia will receive either the drug or a placebo for several weeks. Researchers will measure changes in symptom scales to see if sex influences the treatment's effectiveness.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
NMDA enhancer (NMDAE)
What this could lead to
If successful, this could point toward a more personalized treatment for negative symptoms of schizophrenia, tailored by sex.
What could go wrong
This is an early phase 2 trial with only 90 participants, so results may not apply broadly. The drug may not work better than placebo, and side effects are possible.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Department of Psychiatry, China Medical University Hospital
RECRUITINGTaichung, Taiwan
Contact Phone: •••-•••-•••• Email: •••••@•••••