Could a rectal gel save children with severe malaria in remote villages?
NCT ID NCT06806956
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looks at whether giving a rectal gel (rectal artesunate) followed by three days of malaria pills works as well as the standard injected treatment for young children with severe malaria. It involves about 2,000 children aged 6 months to 5 years in remote areas of Zambia and the Democratic Republic of Congo. The goal is to find a practical treatment option when getting to a hospital is not possible.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Tropical Diseases Research Centre
Ndola, Copperbelt, 10101, Zambia
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University of Kinshasa
Kinshasa, Kinshasa City, Democratic Republic of the Congo
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