Could a rectal gel save children with severe malaria in remote villages?

NCT ID NCT06806956

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This study looks at whether giving a rectal gel (rectal artesunate) followed by three days of malaria pills works as well as the standard injected treatment for young children with severe malaria. It involves about 2,000 children aged 6 months to 5 years in remote areas of Zambia and the Democratic Republic of Congo. The goal is to find a practical treatment option when getting to a hospital is not possible.

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Conditions

The condition(s) this trial relates to.

malaria

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Tropical Diseases Research Centre

    Ndola, Copperbelt, 10101, Zambia

  • University of Kinshasa

    Kinshasa, Kinshasa City, Democratic Republic of the Congo