New tool could help stop malaria spread by reading Parasite's mind

NCT ID NCT06064591

Completed Knowledge-focused Sponsor: Institute of Tropical Medicine, Belgium Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This completed study of 458 people in Burkina Faso aims to develop a tool that estimates how often malaria parasites switch to a form that can spread to mosquitoes. Researchers will measure certain biomarkers in blood samples from people with and without malaria symptoms. The goal is to better predict and ultimately interrupt malaria transmission.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this tool could help predict and reduce malaria transmission by identifying when parasites are most likely to spread.
What could go wrong: This is an observational study, not a treatment trial. The tool is still being developed and validated, so it may not lead to immediate public health changes.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

malaria Plasmodium falciparum malaria

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ASYPTOMATIC PLASMODIUM INFECTION SEVERE MALARIA UNCOMPLICATED MALARIA

Contacts and locations

Locations

Institut de Recherche en Sciences de la Santé - Clinical Research Unit of Nanoro

Nanoro, Burkina Faso
Institute of Tropical Medicine Antwerp

Antwerp, Antwerp, 2000, Belgium
Instituto Nacional de Saúde (INS)

Maputo, Mozambique

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