Can simple reminders keep children safe from malaria after hospital?

NCT ID NCT06601712

Recruiting now Disease control Sponsor: Institut de Recherche Clinique du Benin Source: ClinicalTrials.gov ↗

First seen Aug 12, 2026 · Last updated Aug 13, 2026 · Updated 1 time

Summary

This trial in Benin tests different ways to help caregivers give children a 3-day course of malaria prevention medicine each month for three months after leaving the hospital. The children, all under 10, were hospitalized with severe malaria or severe anemia. Some families get home visits from community health workers, others get SMS or phone reminders, and some get no extra support. The goal is to see which approach improves adherence to the full 9-dose regimen and reduces hospital readmissions.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Post-discharge malaria chemoprevention (PDMC) with adherence support strategies (community health worker home visits or SMS/phone reminders)
What this could lead to: If successful, this could identify the best way to deliver and support malaria prevention after hospital discharge, reducing readmissions and deaths in high-risk children.
What could go wrong: The trial is focused on implementation in one country, and results may not apply elsewhere. Adherence support may not improve outcomes as hoped, and the study is not designed to test the drugs' efficacy directly.

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Conditions

The condition(s) this trial relates to.

anemia malaria prevention target

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

SEVERE ANAEMIA SEVERE MALARIA

Contacts and locations

Locations

Centre Hospitalier Universitaire de la Mere et de l'Enfant Lagune (CHU-MEL)
RECRUITING

Cotonou, Benin
Goho Departmental Hospital Centre
NOT_YET_RECRUITING

Abomey, Benin

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