Antidepressant dose safety checked in seniors with kidney disease
NCT ID NCT07387120
First seen Feb 04, 2026 · Last updated Jun 08, 2026 · Updated 16 times
Summary
This study looked at whether starting a higher dose (50 mg/day) of the antidepressant sertraline is riskier than a lower dose (25 mg/day) for adults aged 65 and older with reduced kidney function. Researchers analyzed health records from over 6,800 people to see if the higher dose led to more hospital visits, emergency room visits, or deaths within 30 days. The goal was to gather safety information, not to test a new treatment.
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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Locations
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London Health Sciences Centre Research Institute
London, Ontario, Canada
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