Balloon that delivers medicine directly to heart arteries could offer Stent-Free option
NCT ID NCT04470934
First seen Jul 16, 2026 · Last updated Jul 17, 2026 · Updated 1 time
Summary
This study evaluates a special balloon coated with sirolimus, a drug that helps prevent arteries from narrowing again after angioplasty. The balloon is used during routine procedures to open blocked heart arteries in people with coronary artery disease. Researchers are tracking how well it works and its safety in real-world use, focusing on whether it reduces heart attacks or the need for repeat treatments.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- a sirolimus-coated balloon catheter that delivers the drug directly to the artery wall during angioplasty
- What this could lead to
- If successful, this could offer a stent-free option for treating coronary artery disease, reducing the need for repeat procedures.
- What could go wrong
- This is an observational study without a comparison group, so results may not prove superiority over existing treatments. Risks include artery injury, blood clots, or the drug not preventing re-narrowing as expected.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
-
Universitätsklinikum Jena
Jena, Thuringia, 07747, Germany
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