Mapping the immune chaos of sepsis to find who needs a boost

NCT ID NCT07698093

First seen Jul 13, 2026 · Last updated Jul 14, 2026 · Updated 1 time

Summary

This study follows 300 adults in intensive care with septic shock to track how their immune systems change over time. Researchers will analyze blood samples taken alongside routine care to measure different types of immune cells. The goal is to understand why some patients develop long-lasting immune suppression, which can lead to secondary infections and worse outcomes. This knowledge could help identify patients who might benefit from future immune-stimulating treatments.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to
If successful, this could point toward new ways to identify which septic shock patients might benefit from immune-boosting therapies.
What could go wrong
This is an observational study, not a treatment trial. It may reveal patterns but cannot prove that any intervention improves outcomes.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Service civilo-militaire d'Anesthésie-Réanimation et Médecine Périopératoire - Groupement Hospitalier Centre

    Lyon, 69437, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Service d'Anesthésie-Réanimation Groupement Hospitalier Nord Hôpital de la Croix Rousse

    Lyon, 69004, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Service d'Anesthésie-Réanimation-Médecine Intensive Groupement Hospitalier Sud Hôpital Lyon Sud - Bâtiment 3B

    Pierre-Bénite, 69495, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Service de Médecine Intensive - Réanimation (MIR) - Groupement Hospitalier Centre

    Lyon, 69437, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Service de Médecine Intensive - Réanimation (MIR) Groupement Hospitalier Nord Hôpital de la Croix Rousse

    Lyon, 69004, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

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