Balloon vs stent: new hope for heart patients?

NCT ID NCT04859985

First seen Nov 01, 2025 · Last updated May 15, 2026 · Updated 23 times

Summary

This study compares two treatments for coronary artery disease: a drug-coated balloon (Selution DEB) and a drug-eluting stent (DES). About 3,300 participants with blocked heart arteries will be randomly assigned to one of the two procedures. The goal is to see which approach better prevents heart-related death, heart attacks, or the need for repeat procedures over 1 to 5 years.

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Contacts and locations

Locations

  • Academic Teaching Hospital Feldkirch

    Feldkirch, Austria

  • Asklepios Kliniken GmbH & Co.

    Hamburg, Germany

  • BG Klinikum Unfallkrankenhaus Berlin

    Berlin, Germany

  • CH La Rochelle

    La Rochelle, France

  • CHU de Nîmes

    Nîmes, France

  • Centre Hospitalier de Pau

    Pau, France

  • Charite Campus Virchow Klinikum

    Berlin, Germany

  • Clinica Mediterranea

    Naples, Italy

  • Clinique Saint Hilaire

    Rouen, France

  • Elisabeth-Krankenhaus

    Essen, Germany

  • Glenfield Hospital

    Leicester, United Kingdom

  • Golden Jubilee National Hospital

    Glasgow, United Kingdom

  • HOCH Health Ostschweiz Kantonsspital St.Gallen

    Sankt Gallen, Switzerland

  • Herzklinikum Ulm

    Ulm, Germany

  • Herzzentrum Dresden GmbH Universitätsklinik

    Dresden, Germany

  • Hospital Alvaro Cunqueiro, University Hospital of Vigo

    Vigo, Spain

  • Hospital Clinico de Barcelona

    Barcelona, Spain

  • Hospital Universitario de La Princesa

    Madrid, Spain

  • Hôpital Cantonal de Fribourg

    Fribourg, Switzerland

  • Hôpital Européen Georges Pompidou

    Paris, France

  • Hôpital Jaques Cartier

    Massy, France

  • Johannes Wesling Klinikum Minden

    Minden, Germany

  • Kardiologisch-Angiologische Praxis • Herzzentrum Bremen

    Bremen, Germany

  • Kepler Universitätsklinikum GmbH

    Linz, Austria

  • Kliniczny Szpital Wojewódzki Nr. 2 w Rzeszowie

    Rzeszów, Poland

  • MEDICLIN Herzzentrum Lahr

    Lahr, Germany

  • Manchester University NHS Foundation Trust

    Manchester, United Kingdom

  • National Heart Centre Singapore (NHCS)

    Singapore, Singapore

  • Norfolk and Norwich University Hospitals

    Norwich, United Kingdom

  • Northern General, Sheffield

    Sheffield, United Kingdom

  • Ospedale Civile Santi Antonio e Biagio e Cesare Arrigo

    Alessandria, Italy

  • Ospedale Sant'andrea

    Vercelli, Italy

  • Ospedale Santa Croce di Moncalieri

    Torino, Italy

  • RKH Kliniken Bruchsal Fürst Stirum Klinik

    Bruchsal, Germany

  • Royal Berkshire Hospital

    Reading, United Kingdom

  • Royal Infirmary of Edinburgh

    Edinburgh, United Kingdom

  • Royal Sussex County Hospital

    Brighton, United Kingdom

  • SIUN sote Hospital and Healthcare center

    Joensuu, Finland

  • SengKang General Hospital

    Singapore, Singapore

  • Szpital Kliniczny Przemienienia Pańskiego UM

    Poznan, Poland

  • Szpital Ministerstwa Spraw Wewnetrznych

    Rzeszów, Poland

  • Tergooi MC

    Hilversum, Netherlands

  • The Royal Bournemouth and Christchurch Hospitals

    Bournemouth, United Kingdom

  • Trent Cardiac Centre, Nottingham City Hospital

    Nottingham, United Kingdom

  • UMC Utrecht

    Utrecht, Netherlands

  • University Heart Center Graz

    Graz, Austria

  • University Hospital Basel

    Basel, Switzerland

  • University Hospital Brno

    Brno, Czechia

  • University Hospital Geneva (HUG)

    Geneva, Switzerland

  • University Hospital Ostrava

    Ostrava, Czechia

  • University Hospital Southampton

    Southampton, United Kingdom

  • University Hospital of Bern

    Bern, Switzerland

  • University Hospitals Bristol

    Bristol, United Kingdom

  • University Hospitals of North Midlands, Royal Stoke University Hospital

    Stoke-on-Trent, Staffordshire, ST4 6QG, United Kingdom

  • University Koeln

    Cologne, Germany

  • University Medical Center Amsterdam

    Amsterdam, Netherlands

  • University Medical Center Groningen

    Groningen, Netherlands

  • University Medical Center Hamburg Eppendorf

    Hamburg, Germany

  • University Zurich

    Zurich, Switzerland

  • Universitätsklinik Augsburg

    Augsburg, Germany

  • Universitätsklinikum Freiburg

    Bad Krozingen, Germany

  • Worcestershire Royal Hospital

    Worcester, United Kingdom

Conditions

Explore the condition pages connected to this study.