New combo therapy aims to boost radioactive iodine success in young thyroid cancer patients
NCT ID NCT06458036
First seen Jan 06, 2026 · Last updated May 05, 2026 · Updated 13 times
Summary
This study tests whether giving a drug called selpercatinib for 6 months before radioactive iodine therapy can improve treatment outcomes in children, teens, and young adults (ages 2-25) with a specific genetic form of thyroid cancer (RET fusion). The goal is to make the cancer absorb more radioactive iodine, potentially leading to better responses and fewer side effects. About 13 participants will be enrolled at the Children's Hospital of Philadelphia.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Children's Hospital of Philadelphia
RECRUITINGPhiladelphia, Pennsylvania, 19104, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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MD Anderson Cancer Center
NOT_YET_RECRUITINGHouston, Texas, 77030, United States
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Seattle Children's Hospital
NOT_YET_RECRUITINGSeattle, Washington, 98105, United States
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St. Jude Children's Research Hospital
RECRUITINGMemphis, Tennessee, 38105, United States
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Conditions
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