Could a simple Self-Swap replace the speculum for cervical cancer screening?

NCT ID NCT06498661

First seen Nov 01, 2025 · Last updated Apr 28, 2026 · Updated 23 times

Summary

This study tests whether women can collect their own vaginal samples for HPV testing as accurately as a doctor can during a pelvic exam. It involves 750 participants referred for colposcopy or cervical procedures. The goal is to see if self-collection is a reliable, more comfortable option to help more people get screened and prevent cervical cancer.

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Contacts and locations

Locations

  • Emory University Hospital/Winship Cancer Institute

    Atlanta, Georgia, 30322, United States

  • Johns Hopkins University/Sidney Kimmel Cancer Center

    Baltimore, Maryland, 21287, United States

  • Louisiana State University Health Science Center

    New Orleans, Louisiana, 70112, United States

  • M D Anderson Cancer Center

    Houston, Texas, 77030, United States

  • Montefiore Medical Center-Einstein Campus

    The Bronx, New York, 10461, United States

  • UNC Lineberger Comprehensive Cancer Center

    Chapel Hill, North Carolina, 27599, United States

  • UPMC-Magee Womens Hospital

    Pittsburgh, Pennsylvania, 15213, United States

  • University of Alabama at Birmingham Cancer Center

    Birmingham, Alabama, 35233, United States

  • University of Cincinnati Cancer Center-UC Medical Center

    Cincinnati, Ohio, 45219, United States

  • University of Miami Miller School of Medicine-Sylvester Cancer Center

    Miami, Florida, 33136, United States

  • University of New Mexico Cancer Center

    Albuquerque, New Mexico, 87106, United States

  • University of Oklahoma Health Sciences Center

    Oklahoma City, Oklahoma, 73104, United States

  • University of Pennsylvania/Abramson Cancer Center

    Philadelphia, Pennsylvania, 19104, United States

  • University of Puerto Rico

    San Juan, 00936, Puerto Rico

  • VCU Massey Comprehensive Cancer Center

    Richmond, Virginia, 23298, United States

Conditions

Explore the condition pages connected to this study.