Could a simple Self-Swap replace the speculum for cervical cancer screening?
NCT ID NCT06611540
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study compares self-collected vaginal samples to clinician-collected samples for HPV testing in 500 people referred for colposcopy. The goal is to see if self-collection is accurate enough to improve cervical cancer screening rates. Participants will provide both types of samples, and researchers will measure how well each detects precancerous changes.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
HPV Self-Collection
What this could lead to
If successful, this could make cervical cancer screening easier and more accessible by allowing people to collect their own samples at home.
What could go wrong
This is an early-stage study focused on accuracy, not on preventing cancer directly. Self-collection may be less sensitive than clinician-collected samples, and results may not apply to all populations.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Emory University Hospital/Winship Cancer Institute
Atlanta, Georgia, 30322, United States
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Huntsman Cancer Institute/University of Utah
Salt Lake City, Utah, 84112, United States
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Minneapolis VA Medical Center
Minneapolis, Minnesota, 55417, United States
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Montefiore Medical Center-Einstein Campus
The Bronx, New York, 10461, United States
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UNC Lineberger Comprehensive Cancer Center
Chapel Hill, North Carolina, 27599, United States
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UT MD Anderson Cancer Center
Houston, Texas, 77030, United States
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University of Cincinnati Cancer Center-UC Medical Center
Cincinnati, Ohio, 45219, United States
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University of Michigan Rogel Cancer Center
Ann Arbor, Michigan, 48109, United States
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University of New Mexico Cancer Center
Albuquerque, New Mexico, 87106, United States
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University of Pennsylvania/Abramson Cancer Center
Philadelphia, Pennsylvania, 19104, United States
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UofL Health Medical Center Northeast
Louisville, Kentucky, 40245, United States