Large study aims to pinpoint cancer return rates and swelling risks after treatment

NCT ID NCT04291612

Recruiting now Knowledge-focused Sponsor: Memorial Sloan Kettering Cancer Center Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Aug 07, 2026 · Updated 3 times

Summary

This study is observing about 1,715 people with early-stage endometrial cancer to see how often the cancer comes back and how often lymphedema (swelling) happens after standard treatment. Participants will have regular check-ups for 36 months. The goal is to gather real-world data to improve future care.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this trial could provide clearer data on recurrence rates and lymphedema risks after standard endometrial cancer treatment, helping doctors and patients make more informed decisions.
What could go wrong: This is an observational study, not testing a new treatment. It cannot prove that any intervention works better than current care. Results may not apply to all patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Carcinoma, Endometrioid endometrial cancer endometrioid adenocarcinoma endometrium neoplasm stage I endometrioid carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ENDOMETRIAL CANCER ENDOMETRIAL CANCER STAGE I ENDOMETRIOID ADENOCARCINOMA

Contacts and locations

Locations

ADVENTHEALTH (Data collection only)
RECRUITING

Orlando, Florida, 32804, United States
Charles University and General University Hospital (Data Collection Only)
TERMINATED

Prague, Czechia
Hartford Healthcare Cancer Institute @ Hartford Hospital
RECRUITING

Hartford, Connecticut, 06102, United States
Houston Methodist Cancer Center (Data Collection Only)
RECRUITING

Houston, Texas, 77030, United States
L'Azienda Sanitaria Universitaria Friuli Centrale
RECRUITING

Udine, Italy
Lehigh Valley Health Network
RECRUITING

Allentown, Pennsylvania, 18103, United States
Mayo Clinic (Data Collection and Data Analysis)
ACTIVE_NOT_RECRUITING

Rochester, Minnesota, 55905, United States
Memorial Sloan Kettering Basking Ridge (All protocol activities)
RECRUITING

Basking Ridge, New Jersey, 07920, United States
Memorial Sloan Kettering Bergen (All protocol activities)
RECRUITING

Montvale, New Jersey, 07645, United States
Memorial Sloan Kettering Cancer Center
RECRUITING

New York, New York, 10065, United States
Memorial Sloan Kettering Commack (All Protocol Activities)
RECRUITING

Commack, New York, 11725, United States
Memorial Sloan Kettering Monmouth (All protocol activities)
RECRUITING

Middletown, New Jersey, 07748, United States
Memorial Sloan Kettering Nassau (All protocol activities)
RECRUITING

Rockville Centre, New York, 11553, United States
Memorial Sloan Kettering Westchester (All protocol activities)
RECRUITING

Harrison, New York, 10604, United States
Miami Cancer Institute Baptist Health South Florida
RECRUITING

Miami, Florida, 33143, United States
OSLO UNIVERSITY HOSPITAL,RIKSHOPITALET (Data Collection Only)
NOT_YET_RECRUITING

Oslo, Norway
OSPEDALE MICHELE E PIETRO (Data Collection Only)
RECRUITING

Ferrera, Italy
Sulaiman Al Habib Medical Group
NOT_YET_RECRUITING

Khobar, Eastern Province, Saudi Arabia

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