Which drug stops TBI seizures best? new study aims to find out
NCT ID NCT06866691
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study compares two common seizure medications, levetiracetam and lacosamide, to see which works better at preventing early seizures after a traumatic brain injury. Researchers will also track side effects like agitation and sedation. The trial plans to enroll 600 adults with moderate to severe brain injuries.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
levetiracetam (Keppra) and lacosamide (Vimpat)
What this could lead to
If successful, this could show which drug better prevents early seizures after a traumatic brain injury with fewer behavioral side effects, helping guide standard care.
What could go wrong
This is a phase 4 study comparing two already-approved drugs, so no new treatment is being discovered. Results may not apply to all brain injury patients, and individual responses vary.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Wake Forest University Health Sciences
RECRUITINGWinston-Salem, North Carolina, 27157, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact