Could a two-drug cocktail prevent post-surgery brain fog in seniors?

NCT ID NCT07151716

First seen Nov 01, 2025 · Last updated May 24, 2026 · Updated 29 times

Summary

This study looks at whether combining two sedatives—dexmedetomidine and esketamine—can reduce delirium (sudden confusion) in older patients recovering in the ICU after surgery. Delirium is common and can lead to worse outcomes. The trial will involve 100 adults aged 60 and older who are expected to stay in the ICU at least one night. Researchers will check for delirium twice daily for up to 7 days.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Peking University First Hospital

    RECRUITING

    Beijing, Beijing Municipality, 100034, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

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