Second shot of smart cells aims to rescue failing hearts
NCT ID NCT07516288
First seen Apr 12, 2026 · Last updated May 16, 2026 · Updated 4 times
Summary
This early-stage study tests whether a second infusion of a patient's own modified immune cells (CAR-DC) can safely improve heart function in people with end-stage dilated cardiomyopathy, a condition where the heart is enlarged and weak. The cells target a protein called FAP to calm harmful inflammation. Only 5 adults who previously received one dose but later worsened will be enrolled. The main goal is to check safety and see if a second dose can help the heart pump better.
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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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