Teen brain injury study seeks to predict hidden mental health risks

NCT ID NCT06370520

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This study follows over 2,500 teens aged 11 to 17 who come to the emergency room with a mild traumatic brain injury (mTBI). Researchers want to see if they develop new or worsening depression or anxiety in the months after injury. Teens and their parents fill out questionnaires about mood, symptoms, and quality of life at the ER visit, then again at one and three months later. The goal is to create a tool that flags those at highest risk, so they can get mental health support sooner.

What this could mean

Our plain-language read of the trial. This is informational only โ€” not medical advice or a prediction.

What this could lead to
If successful, this could lead to a screening tool that helps doctors identify teens at risk for mental health issues after a mild brain injury, enabling early support.
What could go wrong
This is an observational study, not testing a treatment. It may not find clear predictors, and results might not apply to all teens or settings.

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Conditions

The condition(s) this trial relates to.

Brain Concussion brain injury Craniocerebral Trauma Diffuse Axonal Injury head injury injury intracerebral hemorrhage Intracranial Hemorrhage, Traumatic Intracranial Hemorrhages Skull Fractures traumatic brain injury Unconsciousness

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Baylor College of Medicine, Texas Children's Hospital

    RECRUITING

    Houston, Texas, 77030, United States

  • Children's Hospital of Philadelphia

    RECRUITING

    Philadelphia, Pennsylvania, 19104, United States

  • Hasbro Children's Hospital and Brown University

    RECRUITING

    Providence, Rhode Island, 02903, United States

  • The Medical College of Wisconsin, Inc.

    RECRUITING

    Milwaukee, Wisconsin, 53226, United States

  • University of California, Davis Medical Center

    RECRUITING

    Sacramento, California, 95817, United States

  • University of Texas Southwestern Medical Center

    RECRUITING

    Dallas, Texas, 75390, United States

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