Filler combo aims to restore cheek volume after weight loss
NCT ID NCT06351358
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tested whether combining two types of dermal fillers—Sculptra and Restylane—can improve cheek volume, wrinkles, and skin quality in 41 adults with moderate-to-severe cheek aging. Participants had a history of weight loss or were taking GLP-1 medications. They received up to three Sculptra sessions and one or two Restylane injections over 8 weeks. The study measured changes in skin hydration, radiance, elasticity, and thickness, and asked participants about their satisfaction.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Sculptra (poly-L-lactic acid) and Restylane (hyaluronic acid) dermal fillers
What this could lead to
If successful, this combination approach could offer a more effective, longer-lasting option for restoring cheek volume and skin quality in people with midface aging or post-weight-loss changes.
What could go wrong
This was a small, completed study with no control group, so results may not apply broadly. Dermal fillers carry risks like swelling, bruising, or lumpiness, and effects are temporary.
Disclaimer
Read more
Show less
This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for WEIGHT LOSS are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Show contact details
Enter your email to view the contact information for this study.
By submitting, you agree to our Terms of use
Locations
-
Lorenc Aesthetic Plastic Surgery Center
New York, New York, 10028, United States
-
Somenek + Pittman MD: Advanced Plastic Surgery
Washington D.C., District of Columbia, 20037, United States