Could your own cells heal a severed nerve?

NCT ID NCT05541250

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This early-stage trial tests whether injecting a person's own Schwann cells (taken from a leg nerve) into a damaged major nerve is safe. The study enrolls 30 adults with severe sciatic, brachial plexus, or other major nerve injuries. The goal is to see if the cells can be used without causing harm, with a future hope of improving motor and sensory recovery.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Autologous human Schwann cells (one's own nerve-support cells)

What this could lead to

If it works, this could point toward a new way to improve recovery after severe nerve damage, potentially restoring more movement and feeling.

What could go wrong

This is a very early Phase 1 safety trial with only 30 people. It is not yet known if the cells actually help recovery, and there may be unknown side effects from the injection or nerve harvest.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Peripheral Nerve Injuries traumatic neuropathy

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • University of Miami

    RECRUITING

    Miami, Florida, 33136, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact