New nerve graft could spare patients a second surgery
NCT ID NCT07657182
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests whether a processed nerve graft from a donor (Avance Nerve Graft) works as well as using a piece of the patient's own leg nerve to repair damaged nerves in the arm. About 178 adults with upper arm nerve injuries will be randomly assigned to receive either the donor graft or their own nerve. The main goal is to see how well motor and sensory function recovers over two years.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Avance Nerve Graft (a processed human nerve scaffold)
What this could lead to
If successful, this could offer a safe and effective alternative to using a patient's own nerve for repair, avoiding the need for a second surgery and loss of function at the donor site.
What could go wrong
This is a relatively early-phase study with 178 participants, so results may not apply to all nerve injuries. The Avance graft may not perform as well as the patient's own nerve in restoring full function.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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OrthoIndy
RECRUITINGIndianapolis, Indiana, 46260, United States
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••